Publications
Publications list with links at NCBI: https://www.ncbi.nlm.nih.gov/myncbi/ariel.pani.2/bibliography/public/
Andrade-Lopez JM, Pani AM, Wu M, Gerhart J, Lowe CJ (2023) Molecular characterization of nervous system organization in the hemichordate Saccoglossus kowalevskii, PLoS Biology, in press
Pani AM†, Favichia M, Goldstein B (2023) Long-distance Wnt transport in axons highlights cell type-specific modes of Wnt transport in vivo. bioRxiv 2023.05.03.539245; doi: https://doi.org/10.1101/2023.05.03.539245
Gibney TV, Favichia M, Latifi L, Medwig-Kinney TN, Matus DQ, McIntyre DC, Arrigo AB, Branham KR, Bubrig LT, Ghaddar A, Jiranek JA, Liu KE, Marcucci CG, Porter RJ, Pani AM (2023) A simple method to dramatically increase C. elegans germline microinjection efficiency. Developmental Biology, Jul 9;S0012-1606(23)00129-X. doi: 10.1016/j.ydbio.2023.07.003, PMID: 37433390
Costa DS, Kenny-Ganzert IW, Chi Q, Kelley LC, Park K, Garde A, Matus DQ, Park S, Yogev S, Goldstein B, Gibney TV, Pani AM, Sherwood DR (2023) C. elegans anchor cell transcriptome: ribosome biogenesis and endomembrane expansion promote cell invasion. Development, 150, dev201570, PMID: 37039075
Kippenhan JS, Gregory MD, Nash T, Kohn P, Mervis CB, Eisenberg DP, Garvey MH, Roe K, Morris CA, Kolachana B, Pani AM, Sorcher L, Berman KF. (2023) Dorsal visual stream and LIMK1: hemideletion, haplotype, and enduring effects in children with Williams syndrome. Journal of Neurodevelopmental Disorders, 15(1):29 doi: 10.1186/s11689-023-09493-x
Medwig-Kinney TN, Kinney BA, Martinez MAQ, Yee C, Sirota SS, Mullarkey AA, Somineni N, Hippler J, Zhang W, Shen K, Hammell CM, Pani AM, Matus DQ (2022) Transcriptional regulation and repressive condensates modulate a proliferative-invasive cellular switch in vivo. bioRxiv 2022.09.30.510381; doi: https://doi.org/10.1101/2022.09.30.510381
Pani AM, Gibney TV, Medwig-Kinney TN, Matus DQ, Goldstein B (2022) A new toolkit to visualize and perturb endogenous LIN-12/Notch signaling in C. elegans. microPublication Biology, DOI: 10.17912/micropub.biology.000603
Medwig-Kinney TN, Sirota SS, Gibney TV, Pani AM, Matus DQ (2022) An in vivo toolkit to visualize endogenous LAG-2/Delta and LIN-12/Notch signaling in C. elegans. microPublication Biology, DOI: 10.17912/micropub.biology.000602
Lantzsch I, Yu CH, Yazdkhasti H, Lindow N, Szentgyorgyi E, Prohaska S, Pani AM, Srayko M, Furthauer S, Redemann S (2021) Microtubule reorganization during female meiosis in C. elegans. eLife, 10:e58903 DOI: 10.7554/eLife.58903
Adikes RC, Kohrman AQ, Martinez MAQ, Palmisano NJ, Smith JJ, Medwig-Kinney TN, Min M, Sallee MD, Ahmed OB, Kim N, Liu S, Morabito RD, Weeks N, Zhao Q, Zhang W, Feldman JL, Barkoulas M, Pani AM, Spencer SL, Martin BL, Matus DQ (2020) Visualizing the metazoan proliferation-quiescence decision in vivo. eLife, 9:e63265 DOI: 10.7554/eLife.63265
Gordon KL*, Payne SG*, Linden-High LM*, Pani AM, Goldstein B, Hubbard JA, Sherwood DR. (2019) Ectopic germ cells can induce niche-like enwrapment by body wall muscle. Current Biology 29: 823-833.e5
Pani AM, Goldstein B (2018) Direct visualization of a native Wnt in vivo reveals that a long-range Wnt gradient forms by extracellular dispersal. eLife 7:e38325 DOI: 10.7554/eLife.38325. [PDF]
Heppert JK, Pani AM, Roberts AM, Dickinson DJ, Goldstein B (2018) A CRISPR tagging-based screen reveals localized players in Wnt-directed asymmetric cell division. Genetics 208: 1147-1164. [PDF]
Darras S, Fritzenwanker J, Uhlinger K, Farrelly E, Pani AM, Hurley I, Norris R, Osowitz M, Terasaki M, Wu M, Aronowicz J, Kirschner M, Gerhart J, Lowe CJ (2018) Anteroposterior patterning by early canonical Wnt signaling during hemichordate development. PLoS Biology 16: e2003698. [PDF]
Naegeli KM, Hastie E, Garde A, Wang Z, Keeley DP, Gordon KL, Pani AM, Kelley LC, Morrissey M, Chi Q, Goldstein B, Sherwood DR (2017) Cell invasion in vivo via rapid exocytosis of a transient lysosome-derived membrane domain. Developmental Cell 43: 403-417.
Linden LM, Gordon KL, Pani AM, Payne SG, Garde A, Burkholder D, Chi Q, Goldstein B, Sherwood DR (2017) Identification of regulators of germ stem cell enwrapment by its niche in C. elegans. Developmental Biology 429: 271-284. [PDF]
Heppert JK, Dickinson DJ, Pani AM, Higgins CD, Steward A, Ahringer J, Kuhn JR, Goldstein B (2016) Comparative assessment of fluorescent proteins for in vivo imaging in an animal model system. Molecular Biology of the Cell 27: 3385-3394. [Pubmed Central]
Marston DJ*, Higgins CD*, Peters KA, Cupp TD, Dickinson DJ, Pani AM, Moore RP, Cox AH, Kiehart DP, Goldstein B (2016) MRCK-1 drives apical constriction in C. elegans by linking developmental patterning to force generation. Current Biology 26: 2079-2089. [PDF]
Yao Y, Minor PJ, Zhao YT, Jeong Y, Pani AM, King AN, Symmons O, Gan L, Cardoso WV, Spitz F, Lowe CJ, Epstein DJ (2016) Cis-regulatory architecture of a brain signaling center predates the origin of chordates. Nature Genetics 48: 575-580. [Pubmed Central]
Simakov O, Kawashima T, Marletaz F, Jenkins J, Koyanagi R, et. al. 23 of 52 authors (2015) Hemichordate genomes and deuterostome origins. Nature, 527: 459-465. [PDF]
Highlighted by – Dunn CW (2015) Genomics: Acorn worms in a nutshell. Nature 527: 448-449.
Dickinson DJ, Pani AM, Heppert J, Higgins CD, Goldstein B (2015) Streamlined genome engineering with a self-excising drug selection cassette. Genetics 200: 1035-1049. [PDF] [Protocols]
Pani AM, Mullarkey E*, Aronowicz J*, Assimacopoulos S, Grove EA, Lowe CJ (2012) Ancient deuterostome origins of vertebrate brain signalling centres. Nature 483: 289-294. [Pubmed Central]
Highlighted by – Gee H (2012) Developmental biology: a brainy background. Nature 483: 280.
Lowe CJ, Pani AM (2011) Animal evolution: a soap opera of unremarkable worms. Current Biology 21: 151-153. [PDF]
Sobreira TJP, Marlétaz F, Simões-Costa M, Schechtman D, Pereira AC, Brunet F, Sweeney S, Pani A, Aronowicz J, Lowe CJ, Davidson B, Laudet V, Bronner M, de Oliveira PSL, Schubert M, Xavier-Neto J (2010) Structural shifts of aldehyde dehydrogenase enzymes were instrumental for the early evolution of retinoid-dependent axial patterning in metazoans. Proceedings of the National Academy of Sciences USA 108: 226-231. [PDF]
Pani AM, Hobart HH, Morris CA, Mervis CB, Bray-Ward P, Kimberley KW, Rios CM, Clark RC, Gulbronson MD, Gowans GC, Gregg RG (2010) Genome rearrangements detected by SNP microarrays in individuals with intellectual disability referred with possible Williams syndrome. PLoS One 5: e12349. [PDF]
Morris CA, Pani AM, Mervis CB, Rios CM, Kistler DJ, Gregg RG. (2010) Alpha-1-Antitrypsin deficiency alleles are associated with joint dislocation and scoliosis in Williams syndrome. American Journal of Medical Genetics Part C Seminars in Medical Genetics 154C; 299-306. [Pubmed Central]
Hobart HH, Morris CA, Mervis CB, Pani AM, Kistler DJ, Rios CM, Kimberley KW, Gregg RG, Bray-Ward P (2010) Inversion of the Williams syndrome region is a common polymorphism found more frequently in parents of children with Williams syndrome. American Journal of Medical Genetics Part C Seminars in Medical Genetics 154C: 220-228. [Pubmed Central]
Marshall C*, Young E*, Pani AM, Morris C, Freckmann M-L, Lacassie Y, Howard C, Fitzgerald KK, Peippo M, Morris CA, Shane K, Priolo M, Morimoto M, Kondo I, Manquoqlu E, Berker-Karauzum S, Edery P, Hobart HH, Mervis CB, Zuffardi O, Reymond A, Kaplan P, Tassabehji M, Gregg RG, Scherer SW, Osborne LR. (2008) Infantile spasms is associated with deletion of the MAGI2 gene on chromosome 7q11.23-q21.11. American Journal of Human Genetics, 83: 106-111. [PDF]
* equal contributions
Andrade-Lopez JM, Pani AM, Wu M, Gerhart J, Lowe CJ (2023) Molecular characterization of nervous system organization in the hemichordate Saccoglossus kowalevskii, PLoS Biology, in press
Pani AM†, Favichia M, Goldstein B (2023) Long-distance Wnt transport in axons highlights cell type-specific modes of Wnt transport in vivo. bioRxiv 2023.05.03.539245; doi: https://doi.org/10.1101/2023.05.03.539245
Gibney TV, Favichia M, Latifi L, Medwig-Kinney TN, Matus DQ, McIntyre DC, Arrigo AB, Branham KR, Bubrig LT, Ghaddar A, Jiranek JA, Liu KE, Marcucci CG, Porter RJ, Pani AM (2023) A simple method to dramatically increase C. elegans germline microinjection efficiency. Developmental Biology, Jul 9;S0012-1606(23)00129-X. doi: 10.1016/j.ydbio.2023.07.003, PMID: 37433390
Costa DS, Kenny-Ganzert IW, Chi Q, Kelley LC, Park K, Garde A, Matus DQ, Park S, Yogev S, Goldstein B, Gibney TV, Pani AM, Sherwood DR (2023) C. elegans anchor cell transcriptome: ribosome biogenesis and endomembrane expansion promote cell invasion. Development, 150, dev201570, PMID: 37039075
Kippenhan JS, Gregory MD, Nash T, Kohn P, Mervis CB, Eisenberg DP, Garvey MH, Roe K, Morris CA, Kolachana B, Pani AM, Sorcher L, Berman KF. (2023) Dorsal visual stream and LIMK1: hemideletion, haplotype, and enduring effects in children with Williams syndrome. Journal of Neurodevelopmental Disorders, 15(1):29 doi: 10.1186/s11689-023-09493-x
Medwig-Kinney TN, Kinney BA, Martinez MAQ, Yee C, Sirota SS, Mullarkey AA, Somineni N, Hippler J, Zhang W, Shen K, Hammell CM, Pani AM, Matus DQ (2022) Transcriptional regulation and repressive condensates modulate a proliferative-invasive cellular switch in vivo. bioRxiv 2022.09.30.510381; doi: https://doi.org/10.1101/2022.09.30.510381
Pani AM, Gibney TV, Medwig-Kinney TN, Matus DQ, Goldstein B (2022) A new toolkit to visualize and perturb endogenous LIN-12/Notch signaling in C. elegans. microPublication Biology, DOI: 10.17912/micropub.biology.000603
Medwig-Kinney TN, Sirota SS, Gibney TV, Pani AM, Matus DQ (2022) An in vivo toolkit to visualize endogenous LAG-2/Delta and LIN-12/Notch signaling in C. elegans. microPublication Biology, DOI: 10.17912/micropub.biology.000602
Lantzsch I, Yu CH, Yazdkhasti H, Lindow N, Szentgyorgyi E, Prohaska S, Pani AM, Srayko M, Furthauer S, Redemann S (2021) Microtubule reorganization during female meiosis in C. elegans. eLife, 10:e58903 DOI: 10.7554/eLife.58903
Adikes RC, Kohrman AQ, Martinez MAQ, Palmisano NJ, Smith JJ, Medwig-Kinney TN, Min M, Sallee MD, Ahmed OB, Kim N, Liu S, Morabito RD, Weeks N, Zhao Q, Zhang W, Feldman JL, Barkoulas M, Pani AM, Spencer SL, Martin BL, Matus DQ (2020) Visualizing the metazoan proliferation-quiescence decision in vivo. eLife, 9:e63265 DOI: 10.7554/eLife.63265
Gordon KL*, Payne SG*, Linden-High LM*, Pani AM, Goldstein B, Hubbard JA, Sherwood DR. (2019) Ectopic germ cells can induce niche-like enwrapment by body wall muscle. Current Biology 29: 823-833.e5
Pani AM, Goldstein B (2018) Direct visualization of a native Wnt in vivo reveals that a long-range Wnt gradient forms by extracellular dispersal. eLife 7:e38325 DOI: 10.7554/eLife.38325. [PDF]
Heppert JK, Pani AM, Roberts AM, Dickinson DJ, Goldstein B (2018) A CRISPR tagging-based screen reveals localized players in Wnt-directed asymmetric cell division. Genetics 208: 1147-1164. [PDF]
Darras S, Fritzenwanker J, Uhlinger K, Farrelly E, Pani AM, Hurley I, Norris R, Osowitz M, Terasaki M, Wu M, Aronowicz J, Kirschner M, Gerhart J, Lowe CJ (2018) Anteroposterior patterning by early canonical Wnt signaling during hemichordate development. PLoS Biology 16: e2003698. [PDF]
Naegeli KM, Hastie E, Garde A, Wang Z, Keeley DP, Gordon KL, Pani AM, Kelley LC, Morrissey M, Chi Q, Goldstein B, Sherwood DR (2017) Cell invasion in vivo via rapid exocytosis of a transient lysosome-derived membrane domain. Developmental Cell 43: 403-417.
Linden LM, Gordon KL, Pani AM, Payne SG, Garde A, Burkholder D, Chi Q, Goldstein B, Sherwood DR (2017) Identification of regulators of germ stem cell enwrapment by its niche in C. elegans. Developmental Biology 429: 271-284. [PDF]
Heppert JK, Dickinson DJ, Pani AM, Higgins CD, Steward A, Ahringer J, Kuhn JR, Goldstein B (2016) Comparative assessment of fluorescent proteins for in vivo imaging in an animal model system. Molecular Biology of the Cell 27: 3385-3394. [Pubmed Central]
Marston DJ*, Higgins CD*, Peters KA, Cupp TD, Dickinson DJ, Pani AM, Moore RP, Cox AH, Kiehart DP, Goldstein B (2016) MRCK-1 drives apical constriction in C. elegans by linking developmental patterning to force generation. Current Biology 26: 2079-2089. [PDF]
Yao Y, Minor PJ, Zhao YT, Jeong Y, Pani AM, King AN, Symmons O, Gan L, Cardoso WV, Spitz F, Lowe CJ, Epstein DJ (2016) Cis-regulatory architecture of a brain signaling center predates the origin of chordates. Nature Genetics 48: 575-580. [Pubmed Central]
Simakov O, Kawashima T, Marletaz F, Jenkins J, Koyanagi R, et. al. 23 of 52 authors (2015) Hemichordate genomes and deuterostome origins. Nature, 527: 459-465. [PDF]
Highlighted by – Dunn CW (2015) Genomics: Acorn worms in a nutshell. Nature 527: 448-449.
Dickinson DJ, Pani AM, Heppert J, Higgins CD, Goldstein B (2015) Streamlined genome engineering with a self-excising drug selection cassette. Genetics 200: 1035-1049. [PDF] [Protocols]
Pani AM, Mullarkey E*, Aronowicz J*, Assimacopoulos S, Grove EA, Lowe CJ (2012) Ancient deuterostome origins of vertebrate brain signalling centres. Nature 483: 289-294. [Pubmed Central]
Highlighted by – Gee H (2012) Developmental biology: a brainy background. Nature 483: 280.
Lowe CJ, Pani AM (2011) Animal evolution: a soap opera of unremarkable worms. Current Biology 21: 151-153. [PDF]
Sobreira TJP, Marlétaz F, Simões-Costa M, Schechtman D, Pereira AC, Brunet F, Sweeney S, Pani A, Aronowicz J, Lowe CJ, Davidson B, Laudet V, Bronner M, de Oliveira PSL, Schubert M, Xavier-Neto J (2010) Structural shifts of aldehyde dehydrogenase enzymes were instrumental for the early evolution of retinoid-dependent axial patterning in metazoans. Proceedings of the National Academy of Sciences USA 108: 226-231. [PDF]
Pani AM, Hobart HH, Morris CA, Mervis CB, Bray-Ward P, Kimberley KW, Rios CM, Clark RC, Gulbronson MD, Gowans GC, Gregg RG (2010) Genome rearrangements detected by SNP microarrays in individuals with intellectual disability referred with possible Williams syndrome. PLoS One 5: e12349. [PDF]
Morris CA, Pani AM, Mervis CB, Rios CM, Kistler DJ, Gregg RG. (2010) Alpha-1-Antitrypsin deficiency alleles are associated with joint dislocation and scoliosis in Williams syndrome. American Journal of Medical Genetics Part C Seminars in Medical Genetics 154C; 299-306. [Pubmed Central]
Hobart HH, Morris CA, Mervis CB, Pani AM, Kistler DJ, Rios CM, Kimberley KW, Gregg RG, Bray-Ward P (2010) Inversion of the Williams syndrome region is a common polymorphism found more frequently in parents of children with Williams syndrome. American Journal of Medical Genetics Part C Seminars in Medical Genetics 154C: 220-228. [Pubmed Central]
Marshall C*, Young E*, Pani AM, Morris C, Freckmann M-L, Lacassie Y, Howard C, Fitzgerald KK, Peippo M, Morris CA, Shane K, Priolo M, Morimoto M, Kondo I, Manquoqlu E, Berker-Karauzum S, Edery P, Hobart HH, Mervis CB, Zuffardi O, Reymond A, Kaplan P, Tassabehji M, Gregg RG, Scherer SW, Osborne LR. (2008) Infantile spasms is associated with deletion of the MAGI2 gene on chromosome 7q11.23-q21.11. American Journal of Human Genetics, 83: 106-111. [PDF]
* equal contributions